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Pre-mixed electrolyte powders or tablets are the most convenient delivery method
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The compounded formulations that include B12 or glycine do not appear to significantly change the dry mouth profile, though some users anecdotally report that glycine-B12 blends produce slightly fewer side effects overall
Moreover, negative media coverage or reports of adverse events can lead to increased scrutiny from regulatory bodies and public hesitation, hindering acceptance in the mainstream healthcare setting
It also reduces glucagon secretion from pancreatic alpha cells
