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Description
Rate of cardiovascular death, nonfatal myocardial infarction (heart attack), or nonfatal stroke was significantly lower among patients receiving semaglutide than among those receiving placebo

Clinical trials show average weight losses of 15-22% over 68 weeks when combined with lifestyle changes
US Food and Drug Administration (FDA) Approvals of GLP-1 and GLP1/GIP RAs 11,22-34 However, these labels are being expanded to include additional indications for patients with a spectrum of other cardiometabolic conditions, such as obesity, cardiovascular disease, chronic kidney disease, and obstructive sleep apnea

Cost has divided the world into haves and have-nots

Section 503A permits compounding of drug products as customized therapies for identified individual patients whose medical needs cannot be met by commercially available drug products. 503B compounding , on the other hand, is performed at outsourcing facilities, which are subject to stricter FDA oversight, including cGMP requirements, a requirement to register with FDA, periodic FDA inspections and an obligation to submit adverse event reports and other product-specific information to FDA

LH (Luteinizing Hormone): To see if the signal from the pituitary is being suppressed
