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At 48 weeks, the 12 mg group lost a mean of 24.2% of body weight versus 2.1% in the placebo group

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Environmental modifications include maintaining comfortable indoor temperatures (68-72F), using heating pads or warm blankets, and taking warm baths or showers

Differential activation of chemically identified neurons in the caudal nucleus of the solitary tract in nonentrained rats after intake of satiating vs

Vomiting, while less common than nausea, may occur in some patients and can occasionally be severe enough to warrant treatment discontinuation