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By increasing insulin release, reducing glucagon levels, and slowing stomach emptying, this medication helps create a sense of fullness and reduces calorie intake

2024;73(Supplement_1):117-OR

For instance, central administration of GLP-1R agonists increases the ability of insulin to suppress endogenous glucose production (Knauf et al., 2005

If you are in this group, the medication is working

One important distinction: rapid weight loss itself can affect mood
