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And while metformin has been the first-line therapy in treating type 2 diabetes, the FDA announced in 2019 that Rybelsus (semaglutide), a GLP-1, can also be offered as a first-line treatment

It works by mimicking the body's GLP-1 hormone to help control blood sugar levels in diabetes patients

With the three together you can actually make a single molecule, like a master key, that opens multiple doors as effectively as [individual] keys, and achieve superior outcomes. DiMarchi knows these drugs well, having conducted pioneering research on this class of chemicals as far back as the late 1990s while employed at Eli Lilly as group vice president of research and development

How to manage it: Increase fiber intake by eating more vegetables, legumes, and whole grains

^Eligible patients lost an average of 13.6% of their body weight (-31.3 lbs) in a 64-week clinical trial evaluating 25 mg oral semaglutide compared to those on 2.4 mg injectable semaglutide who lost an average of 14.9% of their body weight (-33.6 lbs) in a 68-week clinical trial. Both were paired with diet and exercise