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Clinical trial data shows approximately 25-30% of weight lost consists of lean mass (including muscle) without specific interventions

But if you continue on the medication at any dose, some degree of supplementation is likely still beneficial

However, they also explain why gastrointestinal side effects are among the most commonly reported

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Piperidine: This corrosive chemical strips away protective groups from amino acids, allowing them to couple in the correct sequence and thereby develop into long peptide chains

In a clinical study of 205 participants, those taking Novo Nordisks pill for 64 weeks lost an average of 16.6% of their body weight among participants who remained on treatment