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Subcutaneous semaglutide induced a 5.0 kg reduction in mean body weight after 12 weeks, which was found to be derived predominantly from body fat mass reduction, assessed by air displacement plethysmography

The dosage ranges from 2.5 milligrams (mg) to 15 mg, and is delivered via a pre-filled pen

Insulin Sensitivity - HOMA2-IR reduction: -52.7% vs -36.5% - Fasting insulin: -55.8% vs -35.7% Suggests mechanisms beyond weight loss alone

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Blood vessels that were previously under higher pressure begin to relax, and cardiac output requirements fall

Mounjaro carries a list price of $1,086.37 for each monthly fill in the U.S., but the amount patients pay largely depends on their insurance plan