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Wolever TMS, Tosh SM, Spruill SE, Jenkins AL, Ezatagha A, Duss R, Johnson J, Chu YF, Steinert RE

Those with a personal or family history of medullary thyroid cancer or multiple endocrine neoplasias should not use Mounjaro, which carries a black box warning about the risk of thyroid C-cell tumors

In midbrain areas, such as the substantia nigra and ventral tegmental area, insulin upregulates dopamine transporter expression and reduces excitatory glutamatergic input, decreasing extracellular dopamine levels [90]

Bouret & Simerly, 2004 )

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