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Methods Post-hoc mediation analyses were conducted to evaluate weight-loss dependent and weight-loss independent effects of tirzepatide on SBP reductions across the 5 SURPASS studies

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In this Review, Cowie and Fisher describe the additional mechanisms of benefit of SGLT2 inhibitors, unrelated to improved glycaemic control.

SEMAGLUTIDE (Lyophilised) is a synthetic peptide supplied in lyophilised powder form for laboratory research and analytical purposes