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bjo-2025-328483 DOI: 10.1136/bjo-2025-328483 Cite This Page : ScienceDaily

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Results A reduction in GLP-1 expression was observed in DIO mice with mitochondrial stress responses in the colon enterocytes

This occurs primarily because tirzepatide delays gastric emptying, allowing intestinal bacteria more time to break down sulfur-containing proteins and produce hydrogen sulfide gas

Geddes JR, Ottesen JT, Mehlsen J, Olufsen MS
