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Monitor kidney function regularly if you have pre-existing kidney concerns

21 The MAESTRO-NASH trial 2224 reported that steatohepatitis resolved without worsening of fibrosis in 25.9% of patients receiving resmetirom 80 mg and in 29.9% of those receiving 100 mg, compared with 9.7% in the placebo group, and fibrosis improved without worsening of steatohepatitis in 24.2% and 25.9%, respectively, compared with 14.2% with placebo

The future of GLP-1 research As GLP-1s continue to reshape the treatment of type 2 diabetes and obesity (along with an expanding list of potential indications), real-world evidence will be essential for optimizing their use, ensuring access, and tailoring treatments to the individual needs of patients

Tables 2, 3, 4 and 5 summarize the main preclinical and clinical studies on the effects of DPP-4 inhibitors on bone metabolism

Do not change, adjust, or discontinue any medications without your physician's guidance

Overall, GLP-1RAs once a week tend to be linked with higher incidences of an injection-site reaction than twice-daily exenatide or once-daily liraglutide