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GLP-1 Medications and Mental Health: What Weve Learned Since 2023 December 26, 2025 | Updated from our original September 2023 post In September 2023, I wrote about semaglutide (commonly known by brand names such as Wegovy and Ozempic) in response to a growing number of client questions

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In essence: Foundayo (orforglipron) is a category-defining innovationthe first oral small-molecule GLP-1 receptor agonist proven to drive meaningful, durable weight reduction with easier administration

The tirzepatide enforcement shift The FDA determined that the tirzepatide shortage was resolved, and Eli Lilly demonstrated adequate supply

And it establishes the habit and discipline of defined eating windows before moving to more restrictive protocols