glp 1 agonists and depression GLP-1 Can Be Heaven or Hell Dependent Upon Dopaminergic Genetic/Epigenetic Antecedents[v1] Psychotropic effects of GLP-1R agonists
Description
60 MeissnerW.RemyP.GiordanaC.MaltteD.DerkinderenP.HoutoJ.et al (2024)
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Ueda P, Soderling J, Wintzell V, Svanstrom H, Pazzagli L, Eliasson B, et al
The drug is being marketed under the brand name Lirafit following the approval from the Drug Controller General of India (DCGI)
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doi: 10.1152/ajpregu.1996.271.4.R848 73 LuSCChenMAtanganLKillionEAKomorowskiRChengYet al
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3 Recent reviews also highlight the dorsomedial hypothalamus as an important target for pre-ingestive cognitive satiation, alongside broader hypothalamic and hindbrain circuits that shape meal initiation, satiation, and satiety
![glp 1 agonists and depression GLP-1 Can Be Heaven or Hell Dependent Upon Dopaminergic Genetic/Epigenetic Antecedents[v1] Psychotropic effects of GLP-1R agonists](https://www.jneurosci.org/content/jneuro/45/46/e1375252025/F1.large.jpg?download=true)
Chronic inflammation results in the loss of cardiomyocytes in diabetic hearts
![glp 1 agonists and depression GLP-1 Can Be Heaven or Hell Dependent Upon Dopaminergic Genetic/Epigenetic Antecedents[v1] Psychotropic effects of GLP-1R agonists](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs44220-025-00390-x/MediaObjects/44220_2025_390_Fig1_HTML.png)