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Notably, the HFHFD used in this study contained a higher proportion of fructose compared with conventional diets used in previous models, which was optimized based on our preliminary experiments

A total of 2,474 patient samples along with duplicates and HapMap controls were genotyped, and data on 726,107 variants were generated

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Real-world usage tells a different story, sometimes better, sometimes worse
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Phase 2 data also showed retatrutide reducing liver fat more than would be expected from weight loss alone
