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Although NLY01 was not associated with any improvement in motor or non-motor features of Parkinsons disease compared with placebo, subgroup analyses suggested a potential benefit in young participants with motor manifestations [274]

This reduction was significantly greater than that seen in the placebo group

doi: 10.1523/jneurosci.2212-10.2011 55 SisleySGutierrez-AguilarRScottMDAlessioDASandovalDASeeleyRJ

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