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In a study on Qsymia, people lost up to 10% of their starting body weight after 13 months

/ nonsignificant trend

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Interestingly, tirzepatide also markedly reduced body weight in patients with type 2 diabetes, which led to studies on its efficacy for the treatment of obesity in the absence of type 2 diabetes

The authors used a conjugate of Ex4 and vitamin B 12 to produce a GLP1 receptor agonist without brain penetrance (Borner et al., 2020
