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Diabetes Metab 49(5): 101470

SellHBlherMKltingNSchlichRWillemsMRuppeFet al

These effects were accompanied by increased intratumoral CD4+ T-cell and natural killer (NK) cell frequencies, a shift of CD8+ and conventional CD4+ T cells toward a memory-like phenotype, reduced regulatory T-cell abundance, and improved antigen-presenting cell-associated immune features (111)

Long-term, the 20.2% average weight loss seen in SURMOUNT-5 gives you a reasonable benchmark
Combined Treatment Studies Diabetes and Depression : A systematic review in Diabetes Care explores the bidirectional relationship between diabetes and depression, emphasizing the need for integrated treatment approaches