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doi: 10.1016/j.cmet.2013.04.008 45 NauckMAQuastDRWefersJPfeifferAFH

Tirzepatide is a groundbreaking medication that addresses two major health challenges: type 2 diabetes and obesity

Archived from the original on 28 October 2021

Agent-level network meta-analysis Major adverse cardiovascular events In the agent-level NMA, tirzepatide significantly reduced the risk of MACE compared with placebo (HR 0.81, 95% CI 0.700.94) and with lixisenatide (HR 0.79, 95% CI 0.650.97)

Rather than stopping abruptly, some prescribers recommend gradually extending the interval between doses