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Although this concept has been recently challenged with the publication of clinical trials showing that Liraglutide 34 and Exendin-4 35 enhancement of -cell function was lost after treatment cessation

Moreover, research suggests that higher maternal BMI may also impact fetal development

where this is particularly severe, nonsurgical methods are unlikely to be sufficient to fully address patient needs, and surgery should be discussed as a potential alternative (with nonsurgical procedures as possible adjuncts)

Potential Withdrawal Symptoms Discontinuing tirzepatide can result in withdrawal symptoms due to its effects on blood sugar regulation and appetite control