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As reported by the American Journal of Managed Care, the approval of an oral semaglutide formulation marked the beginning of what many are calling the oral GLP-1 era. In December 2025, the FDA approved the Wegovy (semaglutide) tablet as the first once-daily oral GLP-1 receptor agonist indicated for chronic weight management in adults with obesity or overweight

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doi: 10.1038/nrendo.2009.48
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SGLT-2 inhibitor and GLP-1 receptor agonist treatment for patients with nonalcoholic fatty liver disease and type 2 diabetes mellitus: is their combination the optimal treatment option
