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James Januzzi, MD Although our primary endpoint fell short of statistical significance, there are encouraging signals in these results that increase enthusiasm to further evaluate effects of AT-001 on diabetic cardiomyopathy, saidJames Januzzi, MD, Hutter Family Professor of Medicine atHarvard Medical School, a cardiologist atMassachusetts General Hospital, director of Heart Failure Trials at theBaim Institute for Clinical Researchand the studys lead author

Between-study heterogeneity was very high (I = 99.21%) although sensitivity analysis revealed that the findings were robust