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The list price for popular GLP-1 drugs is roughly $1,000 to $1,200 for a month's supply or $12,000-plus per year

Not only have I reversed my diabetes, but I've also become more active and present with my friends and family

Key tips for underwriting applicants with GLP1 use Immediately look for: Evidence of the underlying diagnosis (as seen in medical claims, EHR, APS) Whether the GLP-1 is FDA-approved or off-label for that condition Signs of medication adherence (12 months, regular fills) Get cautious when: A GLP1 appears without any supporting clinical context Fills are intermittent or recently initiated Theres no alignment between the medication and expected companion therapies (e.g., no CPAP with sleep apnea) Be confident when: The diagnosis is clear The drug is first line and clinically appropriate Use has been stable long enough to confer benefit Kyle Schimek, PharmD Kyle Schimek is a board-certified pharmacist and Clinical Services Manager at Milliman IntelliScript

The combined effect is a sustained reduction in caloric intake that, when paired with lifestyle modification, produces clinically significant and durable weight loss