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doi: 10.1056/NEJMoa1411892 124 ButlerAEJansonJBonner-WeirSRitzelRRizzaRAButlerPC

The microbiome-to-hormone signaling pathway is real

Ozempic/semaglutide is recommended for patients with specific clinical indications, budget considerations, or thin-fat phenotype without high insulin resistance
They also affect the brain

Weight loss improves metabolic markers, but the cellular machinery for processing energy, meaning mitochondrial function, may need separate support, particularly in individuals with long-standing metabolic dysfunction

We know each individual has a unique health and wellness journey
