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The Medicines and Healthcare products Regulatory Agency (MHRA) has warned healthcare professionals to be aware of the potential risk of pulmonary aspiration in patients using glucagon-like peptide-1 (GLP-1) or dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists (GLP-1 RAs), who undergo surgery or procedures with general anaesthesia or deep sedation

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However, no direct link has been found between GLP-1R agonists and higher pulmonary aspiration risk

Additionally, we highlight the gaps for further studies in clinical applications of GLP-1 RAs in aging-related diseases