surmount-1 tirzepatide weight loss percent 72 weeks Medscape | Retatrutide, Eli Lilly's first-in-class triple hormone receptor agonist, delivered meaningful at 80 in all doses in the Tirzepatide as Anti-Obesity Agent

Tirzepatide (Zepbound) was also recently FDA-approved for weight loss, with studies showing it can help patients lose up to 20% of their body weight

Medication Review: Tirzepatide Starting Dose & Titration for Optimal Outcomes May 2026 Learn the recommended starting dose and titration strategy for tirzepatide in this medication review featuring Jennifer Mylod, DNP, from Arizona Arthritis & Rheumatology Associates in Phoenix, Arizona

Always consult with a qualified healthcare provider before considering any medication options

Nausea may appear, especially after dose increases

However, the study team was not able to draw any causal links between the initiation of these therapies and onset of ophthalmic conditions reported but said they could be the effect of rapid hyperglycemia corrections

The fair question is how it compares to naltrexone, the medication built specifically for alcohol