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The combination of improved glycaemic control, weight reduction, and modest lipid improvements may contribute to overall cardiovascular risk reduction

These insights inform realistic expectations but don't predict exact timelineslifestyle, adherence, and dose also determine pace

Characteristics of elderly patients initiating sitagliptin or non-DPP-4-inhibitor oral antihyperglycemic agents: analysis of a cross-sectional US claims database

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Its scientific appeal comes from the three-pathway design