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Aims/hypothesis Regulators worldwide are reviewing safety data on glucagon-like peptide-1 receptor agonists (GLP-1RA), following reports by the Icelandic Medicines Agency in July 2023 of suicidal ideation and self-injury (SIS) in individuals taking liraglutide and semaglutide

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These usually improve after a few days or weeks as the body adjusts

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These results are a reassuring signal for clinicians and patients alike, especially as GLP-1 RAs become central in managing T2DM and obesity