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There is also evidence of the opposing phenomenon therapeutic inertia where there is a delay in intensifying treatment despite the availability of effective options

Accordingly, incretin-based therapies, such as DPP-4 inhibitors and GLP-1 receptor agonists (GLP-1 RAs) that are resistant to degradation by DPP-4, have been introduced in the market within the past decade to overcome and extend the short half-life of the incretin effect

The medication is working

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7) Risk-Taking Behavior Risk-taking behavior has been observed in hungry animals that take more risks searching for food when they are running low on energy [80, 81]