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A real-world retrospective analysis published in Frontiers in Endocrinology confirmed that injectable semaglutide achieves significant weight reduction with mild to moderate gastrointestinal side effects and a discontinuation rate of only 7% among participants

Both sites are clinically appropriate, but many patients find thigh injection less uncomfortable because the area has fewer nerve endings

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In this review I aim to re-examine the contested concept of food addiction as a disease in the context of emerging GLP-1based obesity pharmacotherapies, integrating perspectives from neurobiology, societal impacts, and early evidence for their potential application in other substance-use disorders

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