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In fact, GLP-1 RAs are able to delay gastric emptying and to slow intestinal motility in the gastro-intestinal tract, which enhances the feeling of early satiety at a central level [45]

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Singh K et al

[3] [4] These medications work by mimicking the incretin hormone glucagon-like peptide-1, which enhances insulin secretion, suppresses glucagon release, and significantly reduces appetite primarily through central satiety pathways, with some slowing of gastric emptying (an effect that may attenuate over time)