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doi: 10.1038/s41591-023-02672-2 [DOI] [PMC free article] [PubMed] [Google Scholar] 29.Wang L, Wang Q, Li L, Kaelber DC, Xu R

You cannot look at 2.4 mg semaglutide and 15 mg tirzepatide and think the numbers are proportional

The body begins adapting to incretin receptor activation

Researchers comparing different GLP-1 class compounds consistently find that the triple agonist approach produces the most comprehensive metabolic improvement when all three pathways are measured

For perspective, that level of weight loss was previously achievable only through bariatric surgery