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In the first trial, liraglutide lowered weight by 12 pounds and improved glucose tolerance relative to placebo over 4 months in 103 patients with schizophrenia spectrum disorders (Larsen JR et al, JAMA Psych 2017;74(1):719728)

Diabetes Care 44(11):25892625

In the United States, obesity-attributable healthcare spending reaches USD 260 billion annually

SURMOUNT-1 data showed 22.5% average body weight reduction at this dose over 72 weeks

In Spain and Italy the model is similar, with pharmacy or local health-authority take-back as the main route
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