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One of the most common side effects of GLP-1 medications is fatigue

How Semaglutide Works for Weight Loss Semaglutide mimics glucagon-like peptide-1 (GLP-1), a natural hormone that regulates appetite and blood sugar

All products are third-party tested with certificates of analysis confirming 98%+ purity, and delivery takes 2-4 business days to most Canadian addresses

The insulin sensitivity advantage for tirzepatide is larger than weight loss alone explains (Diabetes, Obesity and Metabolism, 2025), which suggests the GIP component does real metabolic work beyond appetite suppression

Understanding these potential pathways helps contextualize the limited available evidence and identify areas requiring further investigation

Take your GLP-1 medication on the same day each week (for weekly formulations) or at the same time daily (for daily formulations)