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semaglutide was second (HbA1-c: MD: -1.5%

Portal vein blood samples were taken using an insulin syringe with a 30 gauge needle, peripheral blood samples were taken by puncture of the tail vein

doi:10.1016/j.diabet.2015.02.006 61

immortal time bias), and provide adequately robust observational evidence when randomized trials are not feasible or not yet available [33]

Dear Editor, The global prevalence of type 2 diabetes and obesity, affecting over 507 million 1 and 890 million 2 individuals, respectively, underscores the urgent need for more effective treatments