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Avoid prolonged fasting periods, as blood glucose fluctuations can trigger headaches

Common Prior Authorization Criteria BMI documentation: Most states require a documented BMI of 30 or greater, or 27 or greater with at least one weight-related comorbidity (hypertension, type 2 diabetes, dyslipidemia, obstructive sleep apnea) Failed lifestyle modification: Typically 3 to 6 months of documented dietary counseling and physical activity recommendations that did not produce adequate weight loss Step therapy: Some states require patients to try and fail less expensive medications (phentermine, orlistat) before approving GLP-1 coverage Provider qualification: Some Medicaid plans require the prescriber to have completed training in obesity medicine

However, it is apparent that healthy aging can also be promoted by the positive effects of GLP1RA on multiple individual organs that collectively improve physiological homeostasis (Figure 1)

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But theres no one-size-fits-all maintenance dose