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Therefore, therapeutic options that could work in a way other than classic antidepressants are being sought to increase the effectiveness of the treatment

Glucagon-like peptide-1 agonists (GLP-1s) have been in the spotlight as demand has grown to support type 2 diabetes and weight loss

GLP-1 receptor agonists can trigger heartburn and reflux in some patients by slowing stomach emptying and increasing intragastric pressure

Fatigue is one of the most underrated GLP-1 side effects

Secondary outcomes included the incidence of aborted EGDs due to GRC, the effect of concurrent CLN on GRC, and a comparison of GRC risk among different GLP-1 RA agents
