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This study, together with a companion manuscript, shows that in mice, weight loss as a result of GIP receptor antagonism requires and potentiates functional GLP-1 receptor signalling in the brain, explaining how both GIP receptor agonists and antagonists trigger weight loss through different mechanisms.

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Learn about Semeglutide GLP-1 Ozempic Zepbound Wegovy Trulicity for weight loss.

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Incorporating foods like chia seeds, flaxseeds, and whole grains into your diet may help increase GLP-1 levels naturally