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Specifically, central administration of GLP-1R antagonists block LiCl-induced c-Fos, hypophagia, and pica (37, 41)

Calcium is released from intracellular stores following membrane depolarization due to increased sodium-dependent cell excitability and calcium influx, leading to the exocytosis of hormone-containing vesicles

Boxed warnings function less as direct patient alerts and more as signals within the healthcare system, shaping what clinicians prescribe, how pharmacists dispense, and what risks are emphasized in conversation