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Specifically, central administration of GLP-1R antagonists block LiCl-induced c-Fos, hypophagia, and pica (37, 41)

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Calcium is released from intracellular stores following membrane depolarization due to increased sodium-dependent cell excitability and calcium influx, leading to the exocytosis of hormone-containing vesicles

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Boxed warnings function less as direct patient alerts and more as signals within the healthcare system, shaping what clinicians prescribe, how pharmacists dispense, and what risks are emphasized in conversation

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