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[DOI] [PubMed] [Google Scholar] [144].Pinget M, Goldenberg R, Niemoeller E, Muehlen-Bartmer I, Guo H, Aronson R, Efficacy and safety of lixisenatide once daily versus placebo in type 2 diabetes insufficiently controlled on pioglitazone (GetGoal-P), Diabetes, obesity & metabolism, 15 (2013) 10001007
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and S.K
Novo also reported in early 2026 that CagriSema showed superior HbA1c reduction and weight loss vs semaglutide in a Phase 3 diabetes program (REIMAGINE 2)

Effective programs pair GLP-1 therapy with lifestyle change, medication optimization and de-escalation, coaching, side-effect management and care escalation

Klil-Drori, A
