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Gastrointestinal effects during transitions Nausea is the most common side effect of both medications, affecting roughly 44% of semaglutide users and a similar percentage of tirzepatide users in clinical trials

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Research Linking Ozempic to Blindness Research continues to emerge regarding serious side effects of Ozempic and other GLP-1 receptor agonists: January 2026: Patients Who Experienced Vision Loss After Ozempic Can Make Their Case in Federal Court In December of 2025, the Joint Panel on Multidistrict Litigation chose to centralize lawsuits filed by people who took GLP-1 drugs and then were diagnosed with NAION

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