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No significant differences were observed for myocardial infarction, stroke, or revascularization with risk differences of 0.1% (95% CI 1.0 to 0.8%), 0.8% (95% CI 0.2 to 1.7%), and 0.2% (95% CI -0.71.1%), respectively

The trial included 1,407 randomised adults wit
In conclusion, the paper provides evidence that the reduction of GLP-1+ cells is a general feature of ileal and colonic inflammation in mice and humans and is likely due to altered epithelial differentiation driven by changes in cellular metabolism, particularly mitochondrial dysfunction.

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