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According to another analysis [34], the published results, as a rule, show an improvement in some brain parameters (for example, hippocampal connectivity, glucose metabolism in the brain, hippocampal activation according to functional magnetic resonance imaging), but could not demonstrate a strong correlation with cognitive indicators

The trial also showed a slower decline in eGFR and a lower risk of major cardiovascular events in the semaglutide group compared to placebo

C., Perriman, D

Trial data generally support a lower incidence of GI effects with the longer-acting agents (Table 2), and the authors clinical experience suggests fewer such events when using lower doses
This article examines the current evidence, biological mechanisms, and clinical implications of GLP-1 receptor agonists in relation to cognitive function and dementia risk
