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Discussion In this large national cohort study of patients with MASLD and diabetes but without cirrhosis, we observed protective associations between GLP-1 RA use and subsequent development of cirrhosis, cirrhosis complications, and overall mortality

Dual Action Peptides Both Semaglutide and Tirzepatide are therapeutic peptides that mimic natural hormones called incretins , which are released after eating

Patients with previous gastrointestinal medication use were 9% more likely to stop, suggesting vulnerability to common side effects like nausea, vomiting, and diarrhea

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The temporary elevation during active weight loss is part of the normal physiologic response to rapid fat loss

10.2337/dc19-0883 [DOI] [PubMed] [Google Scholar] 27.Mosenzon O, Blicher TM, Rosenlund S, Eriksson JW, Heller S, Hels OH, et al