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glp 1 vs gip Comparison between GLP-1 RA and the GLP-1/GIP dual agonist GLP-1 and GIP receptors signal
Description
Outcomes included changes in left ventricular ejection fraction (LVEF), end-diastolic volume (LVEDV), end-systolic volume (LVESV), global longitudinal strain (GLS), left ventricular mass, left atrial volume (LAV), and NT-proBNP levels

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Certainly, the apparent advantage of tirzepatide, a dual incretin agonist, over GLP-1RA will spark renewed interest in the therapeutic potential of GIP in type 2 diabetes, obesity and related co-morbidities.

Peak GLP-1 increases were significantly higher (~32%) after RYGB at both follow-ups (p<0.05)

Glucagon-like peptide 1 (GLP-1) based therapies have seen a meteoric rise in popularity (about 300%1 increased use between 2018-2023)
