tirzepatide: images/products/tirzepatide-hero.we How Does Tirzepatide Work? |

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According to the letter, some companies have claimed to develop personalized versions of tirzepatide or other GLP-1s and add B12 or other compounds to them

Some were then randomized to receive either additional fast-acting insulin (insulin lispro) or one of three different doses of tirzepatide (5mg, 10 mg, or 15mg)

N Engl J Med 387(3):205216 Jensen TL et al (2024) The body weight reducing effects of Tirzepatide in people with and without type 2 diabetes: a review on efficacy and adverse effects

Meanwhile, all five medications were associated with a reduced risk for anxiety diagnoses in patients with diabetes, with ORs of: 0.87 (95% CI, 0.85-0.88) for liraglutide

The study found there was no difference in the number of adverse gastrointestinal effects between people with and without Type 2 diabetes in the study