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Both represent a step beyond current FDA-approved options

By suppressing NOD-, LRR- and Pyrin domain-containing protein 3 (NLRP3) inflammasome activation, autophagy reduces the secretion of pro-inflammatory cytokines ( e.g ., IL-1, IL-18), thereby mitigating chronic inflammation

10.1016/j.lfs.2020.118645 Life Sci

Glucagon receptors are expressed in peripheral nerve tissue, and activation may alter sensory nerve signaling

doi: 10.1016/j.bmc.2021.116354

Kushner RF, et al
