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Consistent with the greater weight loss effect, significantly greater reductions in BMI, waist and neck circumference were also observed with liraglutide compared with placebo

Dehydration can be caused by the above symptoms, so those taking GLP-1s need to drink more water than the average person to stay hydrated

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NCT03439943

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Available evidence suggests retatrutide may drive substantial fat-mass reduction, and a recent body-composition substudy reported that the proportion of lean-mass loss relative to total weight loss was similar to other obesity treatments