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Results Semaglutide exposure (area under the plasma concentrationtime curve from time zero to 24 h after the tenth dose and maximum concentration after the tenth dose) did not vary in a consistent pattern across the renal function groups

At week 13, significant reductions versus placebo were observed in glycated hemoglobin (HbA1c: 0.87%), body weight (2.54%), systolic blood pressure (SBP: 3.84 mmHg), pulse pressure (3.81 mmHg), high-sensitivity C-reactive protein (hsCRP: 18.08%), and lipid parameters including total cholesterol (7.00%), nonHDL-C (8.02%), and triglycerides (8.15%)

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