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Description
Tirzepatide causes heartburn primarily through delayed gastric emptying, a therapeutic effect of GLP-1 receptor agonism

Initial appetite suppression can be noticed within the first few weeks

Gastroenterology 144 , S732 (2013)

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist originally developed to treat type 2 diabetes

nausea, vomiting, diarrhoea, abdominal pain) are common across the class nausea is likely at initiation and decreases over time

O., Lubner, S