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Administration of a CCK agonist restores reduced fat-induced GIP secretion in GPR120 KO mice, but not in GPR40 KO mice, suggesting that GPR120 regulates fat-induced GIP secretion via CCK, a hormone that regulates bile release and subsequent triglyceride digestion [54] (Fig
Researchers reported that all tested doses achieved significant body-weight reductions compared with placebo over 72 weeks
[DOI] [PubMed] [Google Scholar] 65.Stern J.H., Rutkowski J.M., Scherer P.E

[46] Senescent cells secrete a harmful mix of inflammatory molecules known as the senescence-associated secretory phenotype (SASP)

These discoveries have revolutionised how we approach obesity management, providing new hope to patients struggling with traditional weight-loss methods

Diabetes Metab, 2019
